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diethyl maleate lung glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: Implications for systemic disease and immunosenescence Numbuzin Korean cream
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Although published CYP2D6 turnover parameters for HRM (e.g., kcat = 29.7 min -1 ) did not fully reproduce clinical exposure, model refinement through PK-Sim’s Parameter Identification tool yielded an optimized kcat that better reflected observed in vivo kinetics
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10.1038/nm.2536 21 D'ArcyP.WangX.LinderS
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