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Additionally, it is unknown whether senolytic FOXO4-DRI can be used to treat keloids
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Importantly, of all the metabolites that significantly distinguished +ADT from −ADT group, the only metabolite that significantly correlated with PROMIS-SRI sleep impairment T -scores was androsterone sulfate, which is a metabolic endpoint marker of the effectiveness of ADT in reducing circulating androgens ( via alterations in the androgenic action on SCN circuitry and circadian rhythmicity
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