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Rats exposed to Al-containing aqueous solutions exhibited oxidative damage to hippocampal tissue, alongside increased expression of Nrf2 and its downstream gene NQO1 in hippocampal cells (Lin et al., 2013)
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Specifically, cells in the tumor core exhibit heightened proliferative capacity, whereas those at the tumor periphery are more prone to infiltration, enabling them to penetrate surrounding normal brain tissues [205]
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