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Phosphonate prodrugs: an overview and recent advances - PMC
In mutations specifically involving the IGF1 or IGF1R , GHR function remains intact resulting in possible accentuation of IGF-I-independent GH effects and causing insulin resistance (Rowlinson et al., 2008)
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As of now, the consensus among experts is that more research is needed – particularly well-controlled human studies – before we can fully endorse BPC-157’s use in medicine
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