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Nicotinamide N-Methyltransferase (NNMT) and Liver Cancer: From Metabolic Networks to Therapeutic Targets

A symmetric matrix was applied as the transmission matrix in which, the value of diagonal elements was calculated as follows: where β is a parameter which have been chosen to be the minimum read count which satisfies the condition β(1− p ins ) in which p ins is the empirically calculated insertion probability obtained by regions with more than 9 consecutive TA sites without insertions

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Furthermore, quantifying the loss of floxed alleles predicted the percentage of GLAST-positive cells (astroglia) per brain region

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