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44 Additionally, in patients who are already taking some form of oral B 12 supplementation, demonstrating B 12 deficiency can be a challenge, even when symptoms are typical (including those of neuropathy-like paraesthesia and numbness) as serum B 12 concentrations may be just within, or sometimes above, the “normal” range

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Elderly patients with subclinical hyperthyroidism tendencies Older adults exhibit increased sensitivity and require slow titration with preferential lower targets

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