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The tolerability and safety outcome was the incidence of adverse effects, complication/illness and/or serious medical events due to the study agent as measured by the National Cancer Institute’s (NCI) Common Criteria for Adverse Event Reporting Version 3.0 [14] and by analysis of serum complete blood count and hepatic function from baseline to week 12 (Esoterix™, LabCorp, Cranford, NJ, USA)

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The active compounds, flavonolignans like silymarin, in milk thistle are responsible for its liver-friendly benefits