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Furthermore, gut microbiota studies have been considered the novel approach for understanding gut health problems, and thus, the possible benefits of citrulline and quercetin for gut health should be explored through microbiome evaluation, and the association of the omics analysis at the gene, transcripts, proteins, and metabolite levels, to ascertain the biological effects of citrulline + quercetin in microbiota interactions

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Four other embodiments comprise the enantiomerically enriched mixtures or compositions comprising, respectively, the compounds of Formulas (I), (Ia), (II), (III), (IV), (V), (VI), and (VII), or a pharmaceutically acceptable salt thereof, substantially free of other isomers in each of their respective mixtures