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In this study, phenotypically uniform trophoblast stage-derived mesenchymal stem cells T-MSCs and their exosomes (T-MSCs-Exo) were investigated for their potential to protect DA neurons in PD models

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An animal study in a reserpine-induced fibromyalgia rat model found that nano-pregabalin (N-PG) alleviated FM symptoms by enhancing CNS penetration, restoring neurotransmitter balance (Glut, NE, CGRP), increasing antioxidant enzyme activity (e.g., SOD), inhibiting pro-inflammatory transcription factors (e.g., NF-κB), and reducing apoptosis by decreasing caspase-3 (Casp-3) activation (8, 36)