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Metabolism of acetaminophen (paracetamol) in plants—two independent pathways result in the formation of a glutathione and a glucose conjugate | Environmental Science and Pollution Research | Springer Nature Link

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After oral administration, the strong acidic gastric juice, various digestive enzymes and bile salts in the intestine could lead to mortality of probiotic, which further cause the limited colonization and proliferation ability of probiotics in the GIT 79