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2.1.3 Role of γ-glutamyltranspeptidase (GGT) As mentioned above, GGT is the only enzyme located on the external surface of epithelial cells that is able to hydrolyze the peptidic bond of GSH to provide a continuous source of cysteine through the γ-glutamyl cycle
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This work paved the way to the increased realization that free radicals play a crucial role in activating degradatory pathways leading to loss of muscle mass that has been developed in studies of diaphragm muscle fatigue and degeneration by Gerald Supinski (360, 361, 382), Thomas Clanton (94, 96), and others (211–215, 255, 357)
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