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In parallel, NADPH-induced ROS generation in hyperoxia activates small GTPases [320,321], which in turn activate the MAPK pathway and c-Jun NH2-terminal kinase (JNK) [322], resulting in increased expression of TGF-β1 and production of TNF-α, IL-1β, IL-6 and IL-8 [286,323,324]

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Contenance:60 gélules

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