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Figure 1 from Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities | Semantic Scholar
Many studies have demonstrated that downregulation of EMT-inducing transcription factors including TWIST1 , SNAI1/SNAIL , SNAI2/SLUG , and ZEB1/2 leads to platinum sensitivity, while upregulation leads to platinum resistance (Supplementary Table S1)
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