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Multiple Sclerosis (MS) MS is a chronic, degenerative autoimmune disease of the central nervous system (CNS), accompanied by axonal loss and inflammation contributing to a progressive neurodegenerative process ( CD8+ T cells were the most common T cells found in acute and chronic MS lesions, outnumbering CD4+ T cells by 3–10 fold in chronically inflamed MS plaques (133–135)
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