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By administering it via local injection, miR-5590 is continuously released to induce autophagy in NPCs, subsequently inhibiting cell apoptosis and regulating the metabolic balance within the ECM, thereby hindering the progression of IVDD ( Recent advancements in multifunctional hydrogels are revolutionizing antioxidant therapies for IVDD through innovative strategies, including precise drug delivery, dynamic adaptability, and microenvironment responsiveness
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