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A clinical trial involving sulforaphane supplements noted side effects of flatulence, constipation, and diarrhea.[ref] The clinical trials using sulforaphane can be a bit confusing because some list the amount of sulforaphane and others list broccoli extract amount, which contains more than just sulforaphane

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This slow ramp-up helps the body adjust and reduces the chance of digestive side effects—a strategy you’d recognize if you’re familiar with how Wegovy® or Zepbound® are dosed