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Bañales-Luna, Figueroa-Vega, Marín-Aragón, and colleagues, publishing in Scientific Reports in 2020, reported associations between NNMT, FTO, and IRX3 genetic variants and both BMI and resting energy expenditure in a Mexican cohort — evidence that variation in the NNMT axis tracks with metabolic phenotype in humans, not only in mice
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Strict Use Limitation Not a peptide, medicine, supplement, or consumer product 5-Amino-1MQ is an investigational NNMT inhibitor with a preclinical evidence base
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