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Noise exposure-induced the cerebral alterations: From emerging evidence to antioxidant-mediated prevention and treatment - ScienceDirect

Its primary significance lies in being the rate-limiting precursor for glutathione (GSH), the tripeptide antioxidant that protects every cell in the body against reactive oxygen species, supports hepatic phase II detoxification, and maintains the integrity of the intestinal epithelial barrier.¹˒² Canine research has established that clinically ill dogs have significantly depleted erythrocyte glutathione concentrations compared with healthy controls, and that this depletion correlates with both illness severity and mortality.¹ Supplementation with cysteine-derived compounds has been shown to increase plasma cysteine concentrations and prevent the progressive glutathione decline observed during hospitalisation.³ Beyond its antioxidant role, cysteine contributes to the structural integrity of proteins through disulphide bond formation, supports keratin synthesis for healthy skin and coat, and participates in taurine biosynthesis — another critical nutrient for canine cardiac and neurological health

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Should it be approved for weight loss this year, CagriSema could bring in more than $17 billion by 2032, according to an estimate from Evaluate, more than the around $12 billion predicted for Eli Lilly’s oral GLP-1 candidate orforglipron