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Figure 3 JNK signaling In ovarian cancer, JNK signaling is crucial in driving macrophage polarization from an anti-inflammatory M2 state to a pro-inflammatory state (62)
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In addition, the PERSIAN Organizational Cohort Study in Mashhad (POCM) (n = 4579) indicated that subjects with the highest PHD score were 35% less likely to experience depression than those with the lowest PHD score (OR = 0.65, 95% CI: 0.48–0.88) [69]
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