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However, the administration of pyruvate acid (500 mg/kg, i.p.), which provides an alternative source of ATP production through the TCA cycle, has been shown to decrease dendritic damage, microglia activation, vascular loss, and zinc accumulation [78,79] (Table 1)

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Garshick recommends consulting a board-certified dermatologist about an oral tranexamic acid prescription if topical, over-the-counter products aren't cutting it