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Leucas zeylanica, which is used in traditional medicine for the treatment of GA, can also improve GA inflammation by reducing the metabolite levels through the inhibition of the AA lipoxygenase pathway (225)

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A study on the effects of long-term treatment with CoQ 10 (200 mg/day) plus selenium (200 μg as selenized yeast) in a homogeneous Swedish healthy elderly population ( n = 219) revealed a significant reduction in cardiovascular mortality not only during the 4-year treatment period, but also 10 years later, compared to those taking either a placebo ( n = 222) or were without treatment ( n = 227) (Alehagen et al., 2015, 2016)