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Additionally, ROS activates stress-sensitive kinases (JNK, p38 MAPK) that phosphorylate IRS-2, accelerating its proteasomal degradation and further impairing β-cell survival (Liu et al., 2020)
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[DOI] [PubMed] [Google Scholar] 147.Amenta F., Cavallotti C., Franch F., Ricci A
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