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While the aromatase mechanism includes inducing FAAH transcription via the estrogens as aromatase transforms testosterone to estrogens, the PKA pathway requires inducing phosphorylation of the proteins that trigger FAAH [125]

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VEGFE encodes four splice isoforms: VEGF-E NZ-2 , VEGF-E NZ-7 , VEGF-E NZ-10 and VEGF-E D1701 , which only bind to VEGFR2 and act as pro-angiogenic factors by promoting pathological angiogenesis in sub-cutaneous lesions infected by the virus [38]