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With ageing, altered inflammatory signaling and phagocytic dysfunction lead to changes in the maintenance of homeostasis by microglia, affecting their capacity for immunosurveillance and cellular debris removal (Koellhoffer et al., 2017
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Here, we focus on the four major types of innate immune cells, NK cells, TAMs, DCs, and MDSCs, to give an overview of their epigenetic regulation strategies that bridge cancer courses
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