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Effects of 17β-estradiol and antioxidant administration on oxidative stress and insulin resistance in ovariectomized rats

The pathology of MS lesions is heterogeneous (Lucchinetti et al., 2000) and several patterns suggesting predominant immune-mediated inflammation (pattern I and II) and primary oligodendrogliopathy (pattern III and IV) have been described (Lucchinetti et al., 1996, 2000)

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Potential concerns may include: Injection-site irritation Allergic or immune reactions Contamination or impurities Incorrect labeling or concentration Medication interactions Unknown long-term effects Delayed diagnosis or treatment Financial cost without proven benefit Compounded medications are not FDA approved, meaning the FDA does not verify their safety, effectiveness or quality before they are marketed