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467,468 Table 3 presents notable clinical studies regarding the application of ICIs in the treatment of TNBC
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Metabolic genes that are targets for HIF-1 include LDHA [encoding the M (muscle) form of lactate dehydrogenase), SLC2A1 (encoding GLUT1), PDK1 (encoding pyruvate dehydrogenase kinase 1), FASN (encoding fatty acid synthase), and ACACA (encoding acetyl-CoA carboxylase 1)
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