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Protein tyrosine kinase inhibitors suppress the production of nitric oxide in mixed glia, microglia-enriched or astrocyte-enriched cultures
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AMP-activated protein kinase (AMPK) directly interacts with the core catalytic domain of SIRT1 and mediates phosphorylation of threonine 344 of SIRT1, which directly inhibits its deacetylation activity (81)
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