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Exercise capacity, measured by the 6-minute walk test, showed that 50% of ARA-290 patients could walk at least 25 meters more compared with only 12% of placebo patients
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GSH depletion-dependent cell death was prevented by selective ferroptosis inhibitors (8 μM Fer-1 and 600 nM Lip-1), iron chelator DFO (80 μM), as well as autophagic inhibitors Baf-A1 (75 nM) and 3-MA (10 mM)
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