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(The enzyme GGT can also catalyze a reaction with water or other oligopeptides as the substrate to generate glutamic acid or γ-glutamyloligopeptides and also release cysteinylglycine.) In the cell, γ -glutamyl cyclotransferase (step 2) releases the transported amino acid and “cyclizes” the glutamic acid to form 5-oxoproline (also called pyroglutamic acid)
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