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Excessive production of O 2 •– and its derivatives contributes to damage in cellular components such as lipid peroxidation, protein carbonylation, and DNA oxidation, thereby triggering inflammation and promoting disease progression [126]

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Naturally, the used triple application L-NAME–L-arginine–combined L-NAME and L-arginine and stable gastric pentadecapeptide BPC 157 administration also would need the fMRI and EEG modalities to measure the functional connectivity (i.e., temporal cross-correlations) between brain regions will be preferable to support and understand the presented results in future experiments