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While retaining their binding to cartilage, these fragments were able to carry payloads such as an MMP-cleavable form of viral IL-10 60 and soluble TNF receptor II, 33 enabling the in vivo imaging of murine OA cartilage

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However, when an underlying condition is present, peripheral neuropathy treatment plans may encompass various approaches, including medication, physical therapy, medical devices, nerve blocks, nerve stimulation (neuromodulation), and surgery as a last resort