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Beyond this core list, several other conditions are commonly tied to B12 deficiency: autoimmune gastritis (which damages the parietal cells that produce intrinsic factor), ileal resection (surgical removal of the part of the small intestine where B12 is absorbed), chronic alcoholism , pancreatic insufficiency , nitrous oxide exposure (including recreational use, which inactivates B12), and increased demand during pregnancy and breastfeeding
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Elevated homocysteine levels are associated with an increased risk of heart disease
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