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Baseline bloodwork — CBC, CRP, ferritin, IL-6, cortisol AM, metabolic panel, thyroid function Cardiovascular assessment — heart rate variability, orthostatic vitals if POTS is suspected Gut health markers — stool testing, zonulin, calprotectin if GI symptoms are prominent Mitochondrial function proxies — lactate, organic acids panel if PEM is a primary complaint From there, a typical protocol might be structured as: Phase 1 (Weeks 1–6): Immune and gut foundation Thymosin Alpha-1: 1.6 mg subcutaneous, twice weekly BPC-157: 250–500 mcg daily, route determined by predominant symptom (oral for gut, injectable for systemic) Phase 2 (Weeks 4–12): Tissue repair and cardiovascular recovery TB-500: 2.0–2.5 mg subcutaneous, twice weekly Continue BPC-157 as indicated Phase 3 (Weeks 8–16): Maintenance and metabolic support Taper or pulse doses based on clinical response Add mitochondrial support if fatigue persists (see: Mitochondrial Peptides and Insulin Resistance) These are illustrative dosing ranges based on clinical research and published protocols