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Emily Schromm | The Challenge Wiki | Fandom

The ZDHHC7 palmitoylates NLRP3 on Cys126, and thus mutation of NLRP3 Cys126 would disrupt its localization in the TGN as well as the recruitment and oligomerization of ASCs, inhibiting the activation of the inflammasome (71) ( Figure 3 )

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Although lipid peroxidation and relative regulatory mechanisms have been established as crucial mediators of various RCD, many fundamental problems still remain elusive and will be the potential discoveries to be made in the future