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A glutathione-responsive ferroptotic inducer with elevated labile iron pool and self-supplied peroxide for chemodynamic therapy - ScienceDirect
By improving the accuracy of secondary screening, this approach has the potential to reduce unnecessary colonoscopies and increase follow-up compliance among FIT-positive individuals
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Among them, compound 39 was identified as the most potent BLM inhibitor, having a significantly inhibitory effect on BLM helicase with an IC 50 value of 0.95 μM, which is more powerful than that of the known BLM inhibitor ML216
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