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Five patients with newly diagnosed APL were intravenously administered at a dose of 0.16 mg/kg for 40 min infusion on the first day followed by 18–20 h daily at a very slow rate with an infusion speed of 8 drips/min (Gao et al., 2018)

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Efforts by EDS advocacy groups are underway to educate more practitioners and to encourage research that could eventually convince insurers of these therapies’ value, potentially improving coverage in the future