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3h), 10 million A375 GPX4 WT or GPX4 KO (clone 1) cells were mixed in a 1:1 PBS:matrigel mixture and injected into the left and right flanks of female athymic mice aged 10-12 weeks with a mean body weight of 24 grams (NCR Nude, Taconic), respectively
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As seen with blood cells, a fast high-capacity binding, which was diminished by phloretin, was recorded, suggesting that this metabolite is actively distributed into endothelial cells as well
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