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STAT3 and RoRγ bind to the promoter site of the IL-17 gene, initiating the maturation and IL-17 secretion of Th17 cells
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This neuro-hormone could also elevate levels of antioxidant enzymes (i.e., SOD, CAT, GSH and GPx), and inhibit detrimental effects of NLRP3 inflammasome 659
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