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Interestingly, pretreatment with the antioxidant N -acetyl cysteine (NAC), a precursor of GSH, prevented the lipopolysaccharide induced changes in the biochemical markers of oxidative stress in male fetuses, and the delayed detrimental effects in male offspring, completely restoring both LTP in the hippocampus and spatial recognition performance (Lanté et al
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In the mitochondria, the production of acetate from acetaldehyde leads to increased levels of acetyl-CoA
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