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The underlying pathophysiology reflects hypothalamic-pituitary-testicular axis dysregulation, diminished steroidogenic capacity, and impaired feedback mechanisms, often coinciding with metabolic complications, such as central adiposity and insulin resistance
Xymogen
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It is essential for the activation of proteins such as osteocalcin and Matrix Gla-Protein (MGP), which are involved in bone mineralization and the inhibition of pathological calcification of soft tissues, including joints
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